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ACE2 activator Diminazene Aceturate (DIZE) reverses the inflammatory status provoked by SARS-CoV-2 S protein. (A, B) LPS- induced MIP1a and IL6 expression decreased in THP-1 macrophages pre-treated with DIZE for 6 hours. Data are illustrated in box-and-whiskers and plotted as median (± min, max). Statistical analysis was performed with Kruskal - Wallis test. *p < 0.05.
