Table 1. Patient baseline characteristics and their correlations with the preoperative R-NLR score (n=151).
Clinicopathologic factors | Patients, n (%) | R-NLR score, n (%) | P value | ||
---|---|---|---|---|---|
0 | 1 | 2 | |||
Age (years) | 0.499 | ||||
<60 | 66 (43.71) | 40 (26.50) | 29 (19.21) | 16 (10.6) | |
≥60 | 85 (56.29) | 25 (16.56) | 25 (16.56) | 16 (10.6) | |
Gender | 0.046 | ||||
Male | 98 (64.90) | 35 (23.18) | 40 (26.50) | 9 (5.96) | |
Female | 53 (35.10) | 30 (19.87) | 14 (9.27) | 23 (15.23) | |
Tumor location | 0.130 | ||||
Upper | 59 (39.07) | 33 (21.85) | 17 (11.26) | 9 (5.96) | |
Middle | 42 (27.81) | 13 (8.61) | 18 (11.92) | 11 (7.28) | |
Lower | 50 (33.11) | 19 (12.58) | 19 (12.58) | 12 (7.95) | |
Tumor size (cm) | 0.001 | ||||
<6 | 108 (71.52) | 54 (35.76) | 39 (25.8) | 15 (9.93) | |
≥6 | 43 (28.48) | 11 (7.28) | 15 (9.93) | 17 (11.26) | |
Differentiation | 0.393 | ||||
Well | 23 (15.23) | 8 (5.30) | 7 (4.64) | 8 (5.30) | |
Moderate | 94 (62.25) | 40 (26.50) | 37 (24.50) | 17 (11.26) | |
Poor/mixed | 34 (22.52) | 65 (43.05) | 54 (35.76) | 32 (21.19) | |
T stage | 0.886 | ||||
T3 | 34 (22.52) | 15 (9.93) | 12 (7.95) | 7 (4.64) | |
T4 | 117 (77.48) | 50 (33.11) | 42 (27.81) | 25 (16.56) | |
Lymph node status | 0.669 | ||||
Negative | 43 (28.48) | 20 (13.25) | 13 (8.61) | 10 (6.62) | |
Positive | 108 (71.52) | 45 (29.80) | 41 (27.15) | 22 (14.57) | |
TNM stage | 0.444 | ||||
II | 46 (30.46) | 22 (14.57) | 13 (8.61) | 11 (7.28) | |
III | 105 (69.54) | 43 (28.48) | 41 (27.15) | 21 (13.91) | |
Neurological invasion | 0.497 | ||||
No | 103 (68.21) | 45 (29.80) | 34 (22.52) | 24 (15.90) | |
Yes | 48 (31.79) | 20 (13.25) | 20 (13.25) | 8 (5.30) | |
Vascular invasion | 0.216 | ||||
No | 113 (74.83) | 51 (33.77) | 36 (23.84) | 26 (17.22) | |
Yes | 38 (25.17) | 14 (9.27) | 18 (11.92) | 6 (3.97) | |
Preoperative CA72-4 level (U/mL) | 14.59±49.27 | 15.05±52.21 | 11.16±43.03 | 19.44±50.90 | 0.752 |
Preoperative CEA level (ng/mL) | 7.35±16.10 | 6.98±16.02 | 6.93±13.47 | 8.83±20.30 | 0.845 |
Preoperative CA19-9 level (U/mL) | 43.74±125.99 | 34.64±97.06 | 41.72±113.47 | 65.61±186.21 | 0.521 |
Preoperative NLR level | 2.21±1.17 | 1.43±0.30 | 2.36±0.75 | 3.53±1.53 | <0.001 |
Preoperative RDW-cv level | 13.55±2.03 | 12.48±0.57 | 13.32±1.56 | 16.10±2.44 | <0.001 |
R-NLR, red blood cell distribution width-neutrophil to lymphocyte ratio; CA72-4, carbohydrate antigen 72-4; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; RDW-cv, red blood cell distribution width-variation coefficient.