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. 2021 Jun;12(3):1049–1057. doi: 10.21037/jgo-21-271

Table 1. Patient baseline characteristics and their correlations with the preoperative R-NLR score (n=151).

Clinicopathologic factors Patients, n (%) R-NLR score, n (%) P value
0 1 2
Age (years) 0.499
   <60 66 (43.71) 40 (26.50) 29 (19.21) 16 (10.6)
   ≥60 85 (56.29) 25 (16.56) 25 (16.56) 16 (10.6)
Gender 0.046
   Male 98 (64.90) 35 (23.18) 40 (26.50) 9 (5.96)
   Female 53 (35.10) 30 (19.87) 14 (9.27) 23 (15.23)
Tumor location 0.130
   Upper 59 (39.07) 33 (21.85) 17 (11.26) 9 (5.96)
   Middle 42 (27.81) 13 (8.61) 18 (11.92) 11 (7.28)
   Lower 50 (33.11) 19 (12.58) 19 (12.58) 12 (7.95)
Tumor size (cm) 0.001
   <6 108 (71.52) 54 (35.76) 39 (25.8) 15 (9.93)
   ≥6 43 (28.48) 11 (7.28) 15 (9.93) 17 (11.26)
Differentiation 0.393
   Well 23 (15.23) 8 (5.30) 7 (4.64) 8 (5.30)
   Moderate 94 (62.25) 40 (26.50) 37 (24.50) 17 (11.26)
   Poor/mixed 34 (22.52) 65 (43.05) 54 (35.76) 32 (21.19)
T stage 0.886
   T3 34 (22.52) 15 (9.93) 12 (7.95) 7 (4.64)
   T4 117 (77.48) 50 (33.11) 42 (27.81) 25 (16.56)
Lymph node status 0.669
   Negative 43 (28.48) 20 (13.25) 13 (8.61) 10 (6.62)
   Positive 108 (71.52) 45 (29.80) 41 (27.15) 22 (14.57)
TNM stage 0.444
   II 46 (30.46) 22 (14.57) 13 (8.61) 11 (7.28)
   III 105 (69.54) 43 (28.48) 41 (27.15) 21 (13.91)
Neurological invasion 0.497
   No 103 (68.21) 45 (29.80) 34 (22.52) 24 (15.90)
   Yes 48 (31.79) 20 (13.25) 20 (13.25) 8 (5.30)
Vascular invasion 0.216
   No 113 (74.83) 51 (33.77) 36 (23.84) 26 (17.22)
   Yes 38 (25.17) 14 (9.27) 18 (11.92) 6 (3.97)
Preoperative CA72-4 level (U/mL) 14.59±49.27 15.05±52.21 11.16±43.03 19.44±50.90 0.752
Preoperative CEA level (ng/mL) 7.35±16.10 6.98±16.02 6.93±13.47 8.83±20.30 0.845
Preoperative CA19-9 level (U/mL) 43.74±125.99 34.64±97.06 41.72±113.47 65.61±186.21 0.521
Preoperative NLR level 2.21±1.17 1.43±0.30 2.36±0.75 3.53±1.53 <0.001
Preoperative RDW-cv level 13.55±2.03 12.48±0.57 13.32±1.56 16.10±2.44 <0.001

R-NLR, red blood cell distribution width-neutrophil to lymphocyte ratio; CA72-4, carbohydrate antigen 72-4; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; RDW-cv, red blood cell distribution width-variation coefficient.