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. 2021 Jun;10(6):2750–2761. doi: 10.21037/tau-20-1363

Table 1. Summary of risk-stratified cystoscopic follow-up guidelines following treatment for NMIBC.

Guideline Low risk NMIBC Intermediate risk NMIBC High risk NMIBC
EAU (3) • Cystoscopy at 3 months
• Subsequent cystoscopy 9 months later
• Then annually for 5 years
• Stop follow-up after 5 years if tumour-free
• Patients should have an “in-between (individualised)” follow-up schedule • Cystoscopy and urine cytology at 3 months
• Subsequent follow-up every 3 months for 2 years
• Then every 6 months until 5 years
• Life-long annual cystoscopies thereafter
AUA (4) • Cystoscopy at 3 months
• Subsequent cystoscopy 6–9 months later
• Annually until 5 years
• Shared-decision making about surveillance thereafter
• Cystoscopy at 3 months
• Subsequent cystoscopy and cytology every 3–6 months for 2 years
• Then 6–12 months until 5 years
• Life-long annual cystoscopies thereafter
• Cystoscopy at 3 months
• Subsequent cystoscopy every 3–4 months for 2 years
• Then every 6 months until 5 years
• Life-long annual cystoscopies thereafter
NICE (5) • Cystoscopy at 3 months
• Subsequent cystoscopy at 12 months
• Do not offer prolonged cystoscopic follow-up after 12 months
• Cystoscopy at 3 months
• Subsequent cystoscopy at 9 and 18 months
• Annually thereafter
• Consider discharging patients to primary care if disease-free after 5 years
• Cystoscopy every 3 months for 2 years
• Then every 6 months for another 2 years
• Life-long annual cystoscopies thereafter
NCCN (6) • Cystoscopy at 3 and 12 months
• Then annually for 5 years
• Shared-decision making about surveillance thereafter
• Cystoscopy at 3 months
• Subsequent cystoscopy at 6 and 12 months
• Then every 6 months for 1 year
• Then annually until years 5
• Shared-decision making about surveillance thereafter
• Cystoscopy every 3 months for 2 years
• Then every 6 months for 2 years
• Then annually until 10 years
• Shared-decision making about surveillance thereafter

AUA, American Urological Association; EAU, European Association of Urology; NCCN, National Comprehensive Cancer Network; NICE, National Institute for Health and Care Excellence; NMIBC, non-muscle invasive bladder cancer; MIBC, muscle invasive bladder cancer.