Figure 1. Distinct genomic profiles of cells from individuals of Back versus White ancestries are accompanied by signs of genomic admixture and variation.

1. Principal component analysis (PCA) based on 53,837 single nucleotide polymorphism (SNPs) markers of 62 foreskin donors assessed by microarray chip hybridization (via Illumina Human Omni2.5). PLINK (Package: PLINK1.07) and GCTA analysis tools were used for genetic distance analysis. The first two components (PC1 and PC2) are plotted and explain 5.1% of the variance. Dotted line corresponds to eigenvectors at 0. Each point represents a foreskin donor. Points are labeled and grouped according to self‐reported donors’ country of origin.
2. Admixture analysis of the indicated HKC strains of Black versus White individuals, on the basis of the SNP genotype dataset with the simplest assumption of two ancestries (K = 2). On the y‐axis admixture proportions are represented as gray and black bars. On the x‐axis, individual samples are reported. Dashed lines delimit Black individuals with more than 20% admixture of the other ancestry.