Figure 9.

Biosensors based on DNA assembly‐based stimuli‐responsive systems. a) The working principle of copper ion responsive DNAzyme crosslinked hydrogel. Reproduced with permission.^{[ 294 ]} Copyright 2011, Royal Society of Chemistry. b) Schematic illustration of the analysis of miRNA using the classical tMB. Reproduced with permission.^{[ 74 ]} Copyright 2018, American Chemical Society. c) Schematic presentation of the proximity binding and metal‐ion dependent DNAzyme‐based recycling amplification for electrochemical assay of thrombin. Reproduced with permission.^{[ 295 ]} Copyright 2016, American Chemical Society. d) Working principle of the dual‐fluorophore‐labeled i‐motif nanoprobe. Reproduced with permission.^{[ 296 ]} Copyright 2015, American Chemical Society. e) Schematic showing the AuNP‐dsDNA system, local heating due to laser‐induced photothermal event and subsequent DNA release. Reproduced with permission.^{[ 297 ]} Copyright 2020, American Chemical Society. f) Scheme of DNA tetrahedra that are reconfigurable by adapting dynamic sequences in one arm (i‐motif, T‐Hg²⁺‐T). Reproduced with permission.^{[ 170 ]} Copyright 2012, Wiley‐VCH.