Table 1.

Collective presentation of the clinicopathologic, epidemiologic and A3B immunohistochemical characteristics of the studied cases.

Lesions	Gender	Age (years)	Location	A3B H-Score
OEH (n=13)	5M: 8F	Mean=57.3 Range=30–96	Tongue (n=7) Buccal mucosa (n=3) Mandibular Vestibule (n=2) Palate (n=1)	Median=18.4 Range=1.4–45.4
Low-grade OED (n=43)	25M:18F	Mean=64.1 Range=28–92	Tongue (n=32) Buccal mucosa (n=3) Mandibular vestibule (n=3) Alveolar mucosa/gingiva (n=2) Palate (n=2) Floor of mouth (n=1)	Median=32.4 Range=4.5–94.5
High-grade OED (n=45)	22M:23F	Mean=63.1 Range=35–88	Tongue (n=36) Floor of mouth (n=4) Buccal mucosa (n=2) Mandibular vestibule (n=2) Palate (n=1)	Median=63.1 Range=11.4–108
OSCC (n=46)	22M:24F	Mean=66.2 Range=34–93	Tongue (n=23) Alveolar mucosa/gingiva (n=8) Floor of mouth (n=5) Mandibular vestibule (n=5) Palate (n=4) Lower lip (n=1)	Median=49 Range=10.1–117
HPV+ (p16+) OED (n=13)	12M:1F	Mean=62.8 Range=51–87	Floor of mouth (n=4) Tongue (n=4) Buccal mucosa (n=2) Alveolar mucosa/gingiva (n=1) Base of tongue (n=1) Palate (n=1)	Median=57.9 Range=33.5–144
HPV+ (p16+) OPSCC (n=46)	44M:2F	Mean=59 Range=43–82	Base of tongue (n=21) Tonsils (n=17) Glossotonsillar sulcus (n=8)	Median=60 Range=20.5–171

A3B, APOBEC3B; OEH, oral epithelial hyperplasia; OED, oral epithelial dysplasia; OSCC, oral squamous cell carcinoma; OPSCC, oropharyngeal squamous cell carcinoma