Table 1.
Distribution of patient baseline characteristics.
| Variable | Level | EIO (N = 44) | JBI (N = 30) | P-value | Overall (N = 74) |
|---|---|---|---|---|---|
| Year of surgery, N (%) | Before 2003 | 15 (34) | 9 (30) | 0.49 | 24 (32) |
| 2003–2006 | 12 (27) | 8 (27) | 20 (27) | ||
| 2007–2010 | 10 (23) | 4 (13) | 14 (19) | ||
| After 2010 | 7 (16) | 9 (30) | 16 (22) | ||
| Age (years), N (%) | <40 | 2 (5) | 1 (3) | 0.97 | 3 (4) |
| 40–49 | 6 (14) | 4 (13) | 10 (14) | ||
| 50–59 | 8 (18) | 7 (23) | 15 (20) | ||
| 60+ | 28 (64) | 18 (60) | 46 (62) | ||
| Median (IQR) | 66 (53–71) | 64 (53–71) | 65 (53–71) | ||
| Menopausal status, N (%) | Premenopausal | 7 (16) | 7 (23) | 0.55 | 14 (19) |
| Postmenopausal | 37 (84) | 23 (77) | 60 (81) | ||
| pN, N (%) | pN0 | 16 (36) | 20 (67) | 0.09 | 36 (49) |
| pN1 | 9 (20) | 5 (17) | 14 (19) | ||
| pN2 | 5 (11) | 1 (3) | 6 (8) | ||
| pN3 | 10 (23) | 4 (13) | 14 (19) | ||
| pNX | 4 (9) | 0 | 4 (5) | ||
| pT, N (%) | pT0 | 0 | 3 (10) | 0.14 | 3 (4) |
| pT1 | 21 (48) | 11 (37) | 32 (43) | ||
| pT2 | 15 (34) | 8 (27) | 23 (31) | ||
| pT3/4 | 8 (18) | 8 (27) | 16 (22) | ||
| Tumor grade, N (%) | G1 | 1 (2) | 1 (3) | <0.001 | 2 (3) |
| G2 | 13 (30) | 25 (83) | 38 (51) | ||
| G3 | 22 (50) | 4 (13) | 26 (35) | ||
| Unknown | 8 (18) | 0 | 8 (11) | ||
| Peritumoral vascular invasion, N (%) | No | 32 (73) | 26 (87) | 0.25 | 58 (78) |
| Yes | 12 (27) | 4 (13) | 16 (22) | ||
| Neo-adjuvant treatment, N (%) | No therapy | 38 (86) | 23 (77) | 0.01 | 61 (82) |
| ET | 0 | 1 (3) | 1 (1) | ||
| CT | 1 (2) | 6 (20) | 7 (9) | ||
| CT + ET | 1 (2) | 0 | 1 (1) | ||
| Unknown | 4 (9) | 0 | 4 (5) | ||
| Local treatment, N (%) | Mastectomy w/o RT | 14 (32) | 9 (30) | 0.16 | 23 (31) |
| Mastectomy w RT | 7 (16) | 11 (37) | 18 (24) | ||
| Quadrantectomy w/o RT | 4 (9) | 3 (10) | 7 (9) | ||
| Quadrantectomy w RT | 19 (43) | 7 (23) | 26 (35) | ||
| Adjuvant treatment, N (%) | No therapy | 5 (11) | 10 (33) | 0.007 | 15 (20) |
| ET | 2 (5) | 3 (10) | 5 (7) | ||
| CT | 34 (77) | 12 (40) | 46 (62) | ||
| CT + ET | 2 (5) | 5 (17) | 7 (9) | ||
| Unknown | 1 (2) | 0 | 1 (1) | ||
| Ki67 (%) | Median (IQR) | 22 (13–34) | 10 (10–15) | 0.001 | 15 (10–30) |