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. 2021 Jul 6;78(8):982–992. doi: 10.1001/jamaneurol.2021.2043

Table 2. Frequencies Within Each Glasgow Outcome Scale–Extended (GOSE) Domain for Severe and Moderate Traumatic Brain Injury (TBI) Groups at 2 Weeks and 3, 6, and 12 Months Postinjury.

GOSE domain severity in unweighted analyses No. (%)a
2 wk 3 mo 6 mo 12 mo
Severe (n = 290) Moderate (n = 93) Severe (n = 278) Moderate (n = 84) Severe (n = 282) Moderate (n = 75) Severe (n = 271) Moderate (n = 72)
Vegetative state and death
Vegetative state 68 (23.4) 11 (12) 10 (3.6) 0 4 (1.4) 0 1 (0.4) 0
Died 60 (20.7) 4 (4) 73 (26.3) 9 (11) 78 (27.7) 9 (12) 83 (30.6) 9 (13)
Independence in the home
No assistance 31 (10.7) 36 (39) 115 (41.4) 55 (65) 139 (49.3) 51 (68) 137 (50.6) 50 (69)
Infrequent assistance 5 (1.7) 2 (2) 9 (3.2) 3 (4) 6 (2.1) 2 (3) 5 (1.8) 4 (6)
Frequent assistance 126 (43.4) 40 (43) 71 (25.5) 17 (20) 55 (19.5) 13 (17) 45 (16.6) 9 (13)
Independence in shopping
No assistance 33 (11.4) 36 (39) 115 (41.4) 54 (64) 140 (49.6) 48 (64) 135 (49.8) 47 (65)
Assistance 128 (44.3) 42 (45) 80 (28.8) 21 (25) 60 (21.3) 18 (24) 52 (19.2) 16 (22)
Independence in traveling
No assistance 33 (11.4) 34 (37) 110 (39.6) 54 (64) 139 (49.3) 47 (63) 133 (49.1) 46 (64)
Assistance 128 (44.1) 44 (47) 85 (30.6) 21 (25) 61 (21.6) 19 (25) 54 (19.9) 17 (24)
Workb
No deficit 2 (1.0) 8 (10) 25 (11.8) 21 (29) 57 (26.9) 23 (37) 70 (34.0) 30 (49)
Reduced capacity 3 (1.4) 4 (5) 25 (11.8) 12 (17) 26 (12.3) 12 (19) 20 (9.7) 7 (11)
Limited or unable to work 133 (63.3) 55 (70) 125 (59.2) 34 (47) 94 (44.3) 22 (35) 79 (38.3) 19 (31)
Social and leisure functioning
No deficit 11 (3.8) 16 (17) 56 (20.1) 34 (40) 92 (32.6) 34 (45) 98 (36.2) 34 (47)
A bit less 9 (3.1) 7 (8) 23 (8.3) 10 (12) 24 (8.5) 6 (8) 28 (10.3) 9 (13)
Much less 17 (5.9) 11 (12) 51 (18.3) 15 (18) 38 (13.5) 15 (20) 27 (10.0) 13 (18)
Unable 124 (42.9) 43 (47) 65 (23.4) 16 (19) 46 (16.3) 11 (15) 34 (12.5) 7 (10)
Psychological or interpersonal problems
No disruption 101 (34.9) 38 (41) 122 (43.9) 47 (56) 114 (40.4) 34 (45) 109 (40.2) 35 (49)
Occasional 6 (2.1) 4 (4) 16 (5.8) 5 (6) 25 (8.9) 6 (8) 13 (4.8) 7 (10)
Frequent 16 (5.5) 14 (15) 37 (13.3) 13 (15) 40 (14.2) 18 (24) 43 (15.9) 15 (21)
Constant 38 (13.1) 21 (23) 20 (7.2) 10 (12) 21 (7.4) 8 (11) 22 (8.1) 6 (8)
Other disabling symptoms
No impact 38 (13.1) 12 (13) 49 (17.6) 14 (17) 52 (18.4) 15 (20) 53 (19.6) 18 (25)
Some impact 123 (42.6) 66 (71) 146 (52.5) 60 (72) 148 (52.5) 51 (68) 134 (49.4) 45 (63)
a

Percentages within each domain sum to 100% after adding percentages of individuals in vegetative state and death categories for the group at each time, with the exception of the work domain, which excludes those who did not work preinjury.

b

Work among those who worked preinjury; denominators for these calculations were 210 for those with severe injury at 2 weeks, 79 for those with moderate injury at 2 weeks, 211 for those with severe injury at 3 months, 72 for those with moderate injury at 3 months, 212 for those with severe injury at 6 months, 62 for those with moderate injury at 6 months, 206 for those with severe injury at 1 year, and 7 for those with moderate injury at 1 year.