Table 1.
Clinical status, body composition, and ultrasound parameters of all RA patients.
| Variable | RA patients (n = 84) | Men (n = 18) | Women (n = 66) |
|---|---|---|---|
| Age, yr | 66.5 (59, 74) | 68 (65, 74) | 66 (55, 74) |
| Women percentage, % | 78.6 | 0 | 100 |
| Clinical status | |||
| Disease duration, years | 5.3 (1.2, 11.3) | 4.2 (0.6, 6.6) | 6.1 (1.6, 11.3) |
| Stage, I/II/III/IV | 31/25/14/14 | 6/4/4/4 | 25/21/10/10 |
| Class, 1/2/3/4 | 42/39/3/0 | 10/8/0/0 | 32/31/3/0 |
| CRP, mg/dL | 0.11 (0.05, 0.33) | 0.14 (0.06, 0.23) | 0.11 (0.04, 0.34) |
| MMP3, ng/mL | 74.6 (53.6, 124.9) | 109.4 (75.1, 183.7) | 69.3 (50.4, 104.1) |
| ACPA positive, % | 79.8 | 72.2 | 81.8 |
| RF positive, % | 65.5 | 61.1 | 66.7 |
| DAS28-ESR | 3.5 ± 1.0 | 3.3 ± 0.8 | 3.6 ± 1.0 |
| mHAQ | 0.38 (0.13, 0.75) | 0.125 (0, 0.38) | 0.38 (0.13, 0.88) |
| MTX, mg/week, rate (%) | 8.4 ± 2.9 mg, 84.5% | 7.9 ± 3.4 mg, 72.2% | 8.6 ± 2.8 mg, 87.9% |
| GC, mg/day, rate (%) | 4.4 ± 1.7 mg, 24.2% | 6.3 ± 1.4 mg, 22.2% | 3.9 ± 1.6 mg, 24.2% |
| BIA | |||
| Weight, kg | 52.8 ± 9.5 | 59.8 ± 0.9 | 51.0 ± 9.8 |
| Height, m | 1.56 ± 0.08 | 1.64 ± 0.06 | 1.53 ± 0.07 |
| BMI, kg/m2 | 21.7 ± 3.2 | 22.2 ± 2.8 | 21.6 ± 3.8 |
| Body fat percentage, % | 27.8 ± 7.8 | 22.2 ± 6.2 | 28.8 ± 8.5 |
| ASMI, kg/m2 | 6.4 ± 0.8 | 7.1 ± 0.8 | 6.2 ± 0.7 |
| BMR, kcal | 1052.5 (977, 1159.8) | 1213 (1140, 1294.3) | 1026 (957.3, 1098) |
| Muscle function | |||
| Grip strength, kg | 17.8 (14.1, 21.1) | 19.2 (16.2, 24.2) | 16.9 (10.2, 22.2) |
| Gait speed, m/s | 1.1 ± 0.3 | 1.2 ± 0.2 | 1.1 ± 0.4 |
| Ultrasound | |||
| MT, mm | 27.2 ± 5.3 | 27.5 ± 4.3 | 27.1 ± 5.6 |
| Rectus femoris MT, mm | 14.4 ± 2.9 | 15.3 ± 2.5 | 14.1 ± 3.0 |
| Vastus intermedius MT, mm | 12.8 ± 2.9 | 12.2 ± 2.1 | 12.9 ± 3.0 |
| FT, mm | 9.2 ± 3.8 | 6.8 ± 2.0 | 9.9 ± 3.9 |
Data are shown as mean ± standard deviation (SD) or median (25th, 75th percentile).
RA, rheumatoid arthritis; CRP, C-reactive protein; MMP3, matrix metalloproteinase 3; ACPA, anti-citrullinated protein antibody; RF, rheumatoid factor; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; mHAQ, modified Health Assessment Questionnaire; MTX, methotrexate; GC, glucocorticoid; BIA, bioelectrical impedance analysis; BMI, body mass index; ASMI, appendicular skeletal mass index; BMR, basal metabolic rate; MT, muscle thickness; FT, fat thickness.