Table 2.
Muscle mass parameters of RA patients with and without sarcopenia and obesity.
| Variable | Sarcopenia (n = 19) | No sarcopenia (n = 65) | P-value | Obesity (n = 24) | No obesity (n = 60) | P-value |
|---|---|---|---|---|---|---|
| Age, yr | 77 (64.5, 81.5) | 66 (57, 72) | 0.004‡ | 69.5 (63, 73) | 66 (55.5, 74) | 0.300‡ |
| Women percentage, % | 57.9 | 84.6 | 0.023§ | 70.8 | 81.7 | 0.379§ |
| BIA | ||||||
| Weight, kg | 49.4 ± 8.5 | 53.8 ± 9.6 | 0.076† | 61.7 ± 8.7 | 49.3 ± 7.4 | <0.001† |
| BMI, kg/m2 | 19.9 ± 2.5 | 22.2 ± 3.3 | 0.006† | 25.2 ± 3.0 | 20.3 ± 2.1 | <0.001† |
| Body fat, % | 24.0 ± 7.1 | 28.9 ± 7.8 | 0.016† | 35.9 ± 5.7 | 24.5 ± 6.01 | <0.001† |
| ASMI, kg/m2 | 6.0 ± 0.7 | 6.5 ± 0.8 | 0.005† | 6.8 ± 1.0 | 6.3 ± 0.7 | 0.010† |
| Muscle function | ||||||
| Grip strength, kg | 17.5 (12.8, 22.6) | 18.1 (14.2, 20.7) | 0.549‡ | 17.9 (13.4, 22.6) | 17.7 (14.2, 20.7) | 0.902‡ |
| Gait speed, m/s | 1.1 ± 0.3 | 1.2 ± 0.3 | 0.086† | 1.1 ± 0.3 | 1.2 ± 0.3 | 0.226† |
| Ultrasound | ||||||
| MT, mm | 23.8 ± 4.7 | 28.2 ± 5.1 | 0.001† | 28.7 ± 5.9 | 26.6 ± 5.0 | 0.099† |
| Rectus femoris MT, mm | 13.2 ± 3.0 | 14.7 ± 2.8 | 0.038† | 15.2 ± 3.1 | 14.1 ± 2.8 | 0.109† |
| Vastus intermedius MT, mm | 10.6 ± 2.0 | 13.4 ± 2.8 | <0.001† | 13.5 ± 3.1 | 12.5 ± 2.7 | 0.151† |
| FT, mm | 7.4 ± 1.8 | 9.7 ± 4.0 | 0.016† | 11.8 ± 5.2 | 8.2 ± 2.4 | <0.001† |
Data are shown as mean ± standard deviation (SD) or median (25th, 75th percentile). Continuous variables were analyzed using an unpaired Student's t-test† or the Mann–Whitney U test‡. Categorical variables were analyzed using Fisher's exact test§.
RA, rheumatoid arthritis; BIA, bioelectrical impedance analysis; BMI, body mass index; ASMI, appendicular skeletal mass index; MT, muscle thickness; FT, fat thickness.