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. 2021 Jun;11(3):726–735. doi: 10.21037/cdt-20-977

Table 5. MACE and NACE until discharge after primary PCI in multiple logistic regression analyses stratified by centre.

Variable MACE NACE
Without interaction term With interaction term Without interaction term With interaction term
OR 95% CI OR 95% CI OR 95% CI OR 95% CI
Age 1.05 1.04 to 1.06 1.05 1.04 to 1.06 1.05 1.04 to 1.06 1.05 1.04 to 1.06
Male sex 1.02 0.81 to 1.27 1.01 0.81 to 1.26 0.93 0.75 to 1.16 0.93 0.74 to 1.15
Diabetes 1.85 1.45 to 2.35 1.84 1.45 to 2.34 1.79 1.42 to 2.27 1.79 1.41 to 2.27
Prior MI 1.25 0.90 to 1.74 1.25 0.90 to 1.74 1.26 0.91 to 1.74 1.26 0.92 to 1.74
TIA/stroke 2.16 1.50 to 3.10 2.14 1.49 to 3.07 2.23 1.57 to 3.17 2.21 1.55 to 3.14
Resuscitation 2.96 2.27 to 3.85 2.97 2.28 to 3.86 3.22 2.49 to 4.17 3.23 2.50 to 4.18
Atrial fibrillation 1.54 1.12 to 2.11 1.53 1.12 to 2.09 1.51 1.11 to 2.06 1.50 1.11 to 2.05
Gp2b3a 1.50 1.21 to 1.86 1.50 1.21 to 1.86 1.52 1.23 to 1.87 1.51 1.23 to 1.87
P2Y12 treatment 0.68 0.54 to 0.86 0.68 0.54 to 0.86 0.68 0.54 to 0.85 0.67 0.53 to 0.84
Pain to balloon 1.28 1.03 to 1.58 1.28 1.03 to 1.58 1.37 1.11 to 1.69 1.37 1.12 to 1.69
Major bleeding 4.84 2.33 to 10.06 4.80 2.31 to 9.98
Radial access 0.60 0.47 to 0.78 0.54 0.40 to 0.72 0.59 0.46 to 0.75 0.52 0.40 to 0.70
Shock 8.30 6.50 to 10.59 7.44 5.64 to 9.81 7.91 6.22 to 10.05 7.13 5.44 to 9.35
Radial*shock 1.47 0.92 to 2.36 1.45 0.91 to 2.31

Stratified by centre. Radial*shock represents the interaction term of effect modification. MACE, major adverse cardiovascular events; NACE, net adverse clinical events; PCI, percutaneous coronary intervention; MI, myocardial infarction; TIA, transient ischemic attack; OR, odds ratio; CI, confidence interval.