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. 2021 Jul 7;6:255. doi: 10.1038/s41392-021-00679-0

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The potential inhibitors and therapies to counteract COVID-CS. A variety of inhibitors or drugs have been applied or are under consideration to treat COVID-CS, including those targeting a single pro-inflammatory cytokine or its receptor and related signal pathway. In addition, several treatments such as intravenous immunoglobulin, corticosteroids, traditional Chinese medicine, and CDK7 inhibitor may have the potential to counteract multiple cytokines and pathways involved in COVID-CS. CDK7 cyclin-dependent kinase 7