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. 2021 Jul 6;9(7):e003019. doi: 10.1136/jitc-2021-003019

Figure 2.

Figure 2

IFN-γ ELISpot responses broken out by hTERT dose, IL-12 dose, and tumor type. (A, C, E) Open symbols represent individual patients, the box extends from the 25 th to the 75 th percentile, line inside the box is a the median, and the whiskers extend from the minimum to maximum values. Wilcoxon signs rank test was used to assess significance between the magnitude of IFN-g in patients before (PRE) and after (POST) immunotherapy. The number of patients in each group is displayed below the graph, N. (B, D) The increase over baseline is shown for each group. Wilcoxon ranked sum test was used to assess significance of the increase over baseline between treatment groups. The number of patients, means, medians and ranges of the delta magnitudes for each treatment group are shown. IFN-γ ELISpot responses broken out by hTERT dose, IL-12 dose, and cancer type. hTERT, human telomerase reverse transcriptase; IFN-γ, interferon-γ; IL-12, interleukin 12.