Table 2.
Symptoms, depression, anxiety and QoL of patients in the OSD and Uveitis subgroups
| Overall | OSD | Uveitis | P value | |
| OSDI | 0.066 | |||
| Median (IQR) | 33 (18–56) | 35 (21–68) | 30 (16–50) | |
| % Normal (0–12) | 33 (17%) | 17 (18%) | 16 (16%) | |
| % Mild (13-22) | 28 (14%) | 10 (10%) | 18 (19%) | |
| % Moderate (23-32) | 35 (18%) | 15 (15%) | 20 (21%) | |
| % Severe (33+) | 98 (51%) | 55 (57%) | 43 (44%) | |
| Anxiety score | 0.273 | |||
| Median (IQR) | 4 (2–8) | 5 (3–8) | 4 (2–8) | |
| % No anxiety (≤7) | 147 (74%) | 74 (74%) | 73 (73%) | |
| % Borderline (8-10) | 20 (10%) | 11 (11%) | 9 (9%) | |
| % Anxiety (11+) | 33 (17%) | 15 (15%) | 18 (18%) | |
| Depression score | 0.458 | |||
| Median (IQR) | 5 (3–9) | 6 (3–10) | 5 (2–9) | |
| % No depression (≤7) | 132 (66%) | 63 (63%) | 69 (69%) | |
| % borderline (8-10) | 28 (14%) | 16 (16%) | 12 (12%) | |
| % Depression (11+) | 40 (20%) | 21 (21%) | 19 (19%) | |
| WHOQOL-BREF domain | ||||
| Physical | 14 (12–16) | 14 (11–16) | 14 (12–16) | 0.651 |
| Psychological | 15 (13–17) | 15 (13–17) | 15 (13–17) | 0.414 |
| Social relationships | 16 (13–18) | 16 (13–18) | 16 (13–18) | 0.696 |
| Environment | 16 (14–18) | 16 (14–18) | 16 (13–17) | 0.295 |
Data reported as N (%) or as Median (IQR), as applicable, with p values from Mann-Whitney tests.
Data for the OSDI were only available in N=194 (N=97 OSD and N=97 Uveitis), and the WHO-BREF domains were recorded in N=95–97 OSD and N=95–99 Uveitis.
GCSE, General Certifate of Secondary Education; OSD, ocular surface disease; WHOQOL-BREF, World Health Organisation Quality Of Life Questionnaire.