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. 2021 Jul 7;12:382. doi: 10.1186/s13287-021-02433-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — The effects of SC-CM on endothelial cells. a Proliferation curves of IECs (red) and AECs (blue) in SC-CM and regular medium. b Migrated IECs or AECs in the SC-CM wells and regular medium wells (scale bar = 50 μm). c OD values of the eluted fluid of the cell-migrated membranes in each group. d Capillary-like tube structures formed by IECs or AECs in Matrigel of SC-CM wells and regular medium wells (scale bar = 100). e Capillary-like mesh structure counting of each group. f New vessels formed by IECs perfused with ink in the rat corneas of each group (scale bar = 100). g Vascular segment counting of the new vessels formed by IECs in rat corneas of each group