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. 2021 Jul 7;11:125. doi: 10.1186/s13578-021-00637-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Distinct characteristics of NK and M subpopulations. A, B Nine subclusters were identified after NK cells were combined and clustered. C Heatmap showed the top ten positive marker genes within each cluster. All DEGs are found in Additional file 9. D GO and KEGG analysis were compared in characteristic subclusters of NK cells from three groups. E, F Nine subclusters were identified after M cells were combined and clustered. G Heatmap showed the top ten positive marker genes within each cluster. All DEGs are shown in Additional file 10. H GO and KEGG analysis were compared in characteristic subclusters of M cells from three groups. I Functional enrichment analysis with GO and KEGG analysis of M-2 and M-8