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. 2021 Jul 7;22:198. doi: 10.1186/s12931-021-01788-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Smoke inhalation reduces PO₂ with reciprocal increase in PCO_2. Arterial partial pressure of oxygen (PaO₂) and carbon-dioxide (PaCO₂) levels were measured in SI group at baseline, 2 h, 24 h, and 48 h time points (A). Delta PaO₂ (ΔPaO₂) and delta PaCO₂ (ΔPaCO₂) values between baseline and different time points (B). Mixed venous partial pressure of pressure of oxygen (PmvO₂) and carbon dioxide (PmvCO₂) level were measured in SI group at baseline, 2 h, 24 h, and 48 h time points (C). Delta PmvO₂ (ΔPmvO₂) and delta PmvCO₂ (ΔPmvCO₂) values were calculated between baseline and different time points (D). Delta value for each parameter represented the difference with corresponding baseline values. PaO₂ and PaCO₂ levels were measured at 24 h for n = 8; PmvO₂ and PmvCO₂ levels were not measured at 24 h time line. Smoke inhalation started at 0 h time point. A p value of < 0.05 was considered statistically significant