Table 3.
Association of TG/HDL-C ratio with the absolute change, change rate and slope of baPWV
Model 1 | Model 2 | Model 3 | |||||||
---|---|---|---|---|---|---|---|---|---|
β | 95% CI | P value | β | 95% CI | P value | β | 95% CI | P value | |
Change of baPWV (cm/s) | |||||||||
TG/HDL-C ratio (continuous) | 6.795 | − 1.193 to 14.784 | 0.096 | 4.934 | − 3.684 to 13.552 | 0.062 | 37.057 | 7.85–66.264 | 0.013 |
Quartile 2 (ref: quartile 1) | 70.320 | 21.037–119.604 | 0.005 | 68.883 | 19.964–117.802 | 0.006 | 75.317 | 24.101–126.534 | 0.004 |
Quartile 3 | 83.153 | 34.299–132.007 | 0.001 | 89.453 | 38.544–140.362 | 0.001 | 84.036 | 25.516–142.556 | 0.005 |
Quartile 4 | 131.912 | 82.542–181.282 | < 0.001 | 142.938 | 78.525–207.35 | < 0.001 | 133.420 | 51.949–214.891 | 0.001 |
P for trend | < 0.001 | < 0.001 | 0.002 | ||||||
Change rate of baPWV (cm/s/year) | |||||||||
TG/HDL-C ratio (continuous) | 2.587 | 0.115–5.06 | 0.040 | 1.880 | − 0.801 to 4.562 | 0.169 | 9.768 | 0.547–18.989 | 0.038 |
Quartile 2 (ref: quartile 1) | 14.121 | − 1.149 to 29.392 | 0.070 | 13.621 | − 1.616 to 28.857 | 0.080 | 19.486 | 3.325–35.646 | 0.018 |
Quartile 3 | 23.979 | 8.842–39.117 | 0.002 | 25.543 | 9.687–41.399 | 0.002 | 29.615 | 11.15–48.08 | 0.002 |
Quartile 4 | 38.237 | 22.94–53.534 | < 0.001 | 40.369 | 20.307–60.431 | < 0.001 | 43.511 | 17.804–69.217 | 0.001 |
P for trend | < 0.001 | < 0.001 | 0.001 | ||||||
Slope of baPWV | |||||||||
TG/HDL-C ratio (continuous) | 2.253 | − 0.089 to 4.595 | 0.060 | 4.507 | 1.425–6.048 | 0.045 | 7.973 | 0.801–22.317 | 0.035 |
Quartile 2 (ref: quartile 1) | 12.212 | − 2.264 to 26.687 | 0.098 | 11.300 | − 3.154 to 25.754 | 0.126 | 15.465 | 0.078–30.852 | 0.049 |
Quartile 3 | 21.636 | 7.287–35.986 | 0.003 | 21.977 | 6.935–37.019 | 0.004 | 24.296 | 6.715–41.877 | 0.007 |
Quartile 4 | 33.088 | 18.587–47.589 | < 0.001 | 32.178 | 13.146–51.21 | 0.001 | 33.496 | 9.02–57.972 | 0.007 |
P for trend | < 0.001 | < 0.001 | 0.004 |
Model 1: adjusted age and sex; Model 2: age, sex, BMI, smoking status, drinking status, physical activity, diabetes, dyslipidaemia, baPWV at baseline, and MAP at baseline and follow-up; Model 3: Model 2 plus HDL-C, triglyceride, PBG, LDL-C, eGFR, uric acid, homocysteine, and use of antidiabetic, lipid-lowering, or antihypertensive medications at baseline and follow-up