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. 2021 Jul 7;20:65. doi: 10.1186/s12944-021-01491-z

Table 1.

Gut microbiota differences in obese human and rodent cohorts, preoperative bariatric dietary cohort, post-bariatric surgery human and rodent cohorts, post-allogenic FMT cohort

Cohort Microbiota Findings
Obese cohort [10, 11, 22, 2932]

Rikenellaceae and Christensenellaceae

Bifidobacterium, Oscillospira and Akkermansia

Obese cohort [33] Alistipes finegoldii and Alistipes senegalensis
Obese cohort [34] Alistipes = marker of persistent weight loss success
Obese cohort [11, 35] ↓ Faecali prausnitzii
Obese cohort [21, 32, 36] Weight loss ↑ Faecali prausnitzii, Akkermansia and Christensenellaceae
Obese cohort [37] ↑ Prevotellaceae, Coriobacteriaceae, Erysipelotrichaceae, and Alcaligenaceae
Elevated BMI [38, 39] Roseburia
Obese cohort [40] Eubacterium dolichum
Obese cohort [37] ↑ H2-producing bacteria; (Prevotellaceae, certain groups within the Firmicutes and Archaea)
Obese cohort [11, 26]

↑ gram-negative microbes

↑ Fusobacterium, Escherichia-Shigella, Pseudomonas and Campylobacter

Obese children and overweight women [30, 41] Staphylococcus aureus
Obese cohort on preoperative diet [42]

Streptococcaceae and Ruminococcaceae

Rikenellaceae and Bifidobacteriaceae

Post-bariatric surgery [37, 42, 43]

↑ Gammaproteobacteria (Enterobacteriaceae)

↓ Firmicutes (Clostridium difficile, Clostridium hiranonis, and Gemella sanguinis)

↓ methanogens

Post-bariatric surgery [43, 44] Escherichia, Klebsiella, and Pseudomonas
Six months post-bariatric surgery [42]

Streptococcaceae and Veillonellaceae

Bifidobacteriaceae

Rodent model – post bariatric surgery [45]

↑ Bacteroidetes, Verrucomicrobia, and Proteobacteria

Alistipes, Akkermansia, and Escherichia

Rodent model – post bariatric surgery [46]

↑ Proteobacteria (Enterobacter hormaechei)

↓ Firmicutes and Bacteroidetes

Allogenic FMT recipients [47] Roseburia intestinalis