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. Author manuscript; available in PMC: 2021 Aug 15.

Published in final edited form as: Stat Med. 2020 May 4;39(18):2423–2436. doi: 10.1002/sim.8546

Figure 3: — The bar-plots show the power to detect the mediating set when using the TS (yellow), MIN (green), MARG (orange), LIN (red), and QUAD (brown) procedures. The baseline scenario includes $m_{s} =$ 20 biomarkers per set, $q =$ 20 disjoint sets, $q_{m} =$ 1 mediating set, $q_{O D} =$ 0 one-dimensional sets, $q_{T D} =$ 0 two-dimensional sets, $m_{M} =$ 3 mediating biomarkers, $m_{E} =$ 0 noise-biomarkers, and a correlation of $ρ_{M} =$ 0. We evaluate the effect of varying a single parameter, keeping all other parameters set to their baseline value.