Table 2:

Individual biomarker results for Lysine metabolism group pathway

Metabolite	P-value for association with risk of breast cancer	P-value for association with BMI
2-Aminoadipate	0.43	5.3∙10−4
3-Methylglutarylcarnitine-1*	9.5∙10−5	2.0∙10−8
3-Methylglutarylcarnitine-2	0.02	0.31
Glutarate pentanedioate	0.82	0.96
Lysine	0.35	0.25
N6-Trimethyl-L-lysine	0.13	0.02
N2-Acetyl-L-lysine	0.28	0.09
N6-Acetyl-L-lysine	0.17	0.55
Pipecolate	0.64	0.26
3-Methylglutaconate	0.62	0.82

^*Metabolite discovered by TS and MIN to mediate effect of BMI