Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Approved combinatorial therapies of anti-angiogenic agents and immune checkpoint inhibitors.
| Tumor | Anti-PD1 Ab | Anti-PDL1 Ab | Anti-VEGF Ab | Anti-angiogenic TKi | Combination approval |
|---|---|---|---|---|---|
| LUAD | — | Atezolizumab | Bevacizumab | — | + |
| HCC | — | Atezolizumab | Bevacizumab | — | + |
| RCC | Pembrolizumab | — | — | Axitinib | + |
| Nivolumab | — | — | Axitinib | + | |
| — | Avelumab | — | Cabozantinib | + |
Ab, antibody; HCC, hepatocellular carcinoma; LUAD, lung adenocarcinoma; RCC, renal cell carcinoma; TKi, tyrosine kinase inhibitor.
