Skip to main content
. 2021 Apr 9;27:594724. doi: 10.3389/pore.2021.594724

TABLE 3.

The relationship between Beclin-1 and Bcl-2 expression with clinicopathological features of ESCC.

Pathologic parameter Case n Beclin-1 expression χ 2 p-value Bcl-2 expression χ 2 p-value
High n (%) Low n (%) High n (%) Low n (%)
Gender 0.54 >0.05 0.15 >0.05
 Male 65 24 (36.92) 41 (63.08) 36 (55.38) 29 (44.62)
 Female 37 11 (29.73) 26 (70.27) 19 (51.35) 18 (48.65)
Age 1.07 >0.05 1.07 >0.05
 ≤60 33 9 (27.27) 24 (72.73) 14 (42.42) 19 (57.58)
 >60 69 26 (37.68) 43 (62.32) 41 (59.42) 28 (40.58)
Tumour diameter 0.37 >0.05 2.6 >0.05
 <3 cm 57 21 (36.84) 36 (63.16) 34 (59.65) 23 (40.35)
 ≥3 cm 45 14 (31.11) 31 (68.89) 21 (46.67) 24 (53.33)
Differentiation 3.5 >0.05 1.83 >0.05
 Well and moderate 60 25 (41.67) 35 (58.33) 29 (48.33) 31 (51.67)
 Poor 42 10 (23.81) 32 (76.19) 26 (61.90) 16 (38.10)
Pathological stage 6.18 <0.05 7.28 <0.01
 I–II 44 21 (47.73) 23 (57.27) 17 (38.64) 27 (61.36)
 III–IV 58 14 (24.14) 44 (75.86) 38 (65.52) 20 (34.48)
Lymph node 7.32 <0.01 7.17 <0.01
 Positive 70 18 (25.71) 52 (74.29) 44 (62.86) 26 (37.14)
 Negative 32 17 (53.13) 15 (46.87) 11 (34.38) 21 (65.62)
Depth of invasion 0.86 >0.05 5.37 <0.05
 T1, T2 46 18 (39.13) 28 (60.87) 19 (41.30) 27 (58.70)
 T3, T4 56 17 (30.36) 39 (69.64) 36 (64.29) 20 (35.71)

P < 0.05 was considered statistically significant. χ2 test for categorical variables.