TABLE 5.
The comparison of invasiveness of EC9706 cells in relation to expression of Beclin-1 and Bcl-2.
| Groups | Bcl-2 expression a , % | Beclin-1 expression a , % | Number of invasive cells |
|---|---|---|---|
| Control | 28.00 ± 2.00 | 30.00 ± 2.65 | 243.32 ± 38.23 |
| si-Bcl-2 | 31.33 ± 1.53 | 33.00 ± 2.00 | 225.36 ± 28.16 |
| si-Beclin-1 | 28.67 ± 1.53 | 32.00 ± 2.00 | 235.36 ± 31.26 |
| pcDNA Bcl-2 + pcDNA Beclin-1 | 66.33 ± 2.08 | 73.67 ± 1.53 | 52.65 ± 12.24* |
| pcDNA Beclin-1 + si-Bcl-2 | 30.00 ± 2.00 | 80.33 ± 2.08 | 240.46 ± 32.18 |
| pcDNA Bcl-2 + si-Beclin-1 | 64.67 ± 4.04 | 30.67 ± 1.53 | 381.97 ± 32.31* |
| si-Bcl-2 + si-Beclin-1 | 30.67 ± 1.53 | 32.33 ± 1.53 | 242.12 ± 36.23 |
a
Mean ± standard deviation, relative to GAPDH; *p < 0.01 vs. untransfected control group, calculated with one-way ANOVA analysis of variance.