. 2021 Apr 21;27:629993. doi: 10.3389/pore.2021.629993

TABLE 4.

Univariate Cox regression analysis of the impact of circulating biomarkers on disease specific survival in the combined thymic carcinoma and neuroendocrine tumor cohort.

		Carcinoma and neuroendocrine tumors			Carcinoma
		HR	95% CI	p	HR	95% CI	p
CRP	>1 mg/dl	1	0.47–5.21	0.471	1	0.43–7.04	0.433
CRP	<1 mg/dl	1.56	0.47–5.21	0.471	1.74	0.43–7.04	0.433
WBC	>7 × 10⁹/L	1	1.19–15.63	0.026	1	1.10–23.81	0.035
WBC	<7 × 10⁹/L	4.33	1.19–15.63	0.026	5.21	1.10–23.81	0.035
LDH	<240 U/L	1	0.85–6.26	0.102 ^a	1	0.91–11.63	0.071 ^b
LDH	>240 U/L	2.30	0.85–6.26	0.102 ^a	3.24	0.91–11.63	0.071 ^b

HR–hazard ratio; CI–confidence interval;

^{^a}

p = 0.0185 with Gehan-Breslow-Wilcoxon test.

^{^b}

p = 0.0299 with Gehan-Breslow-Wilcoxon test.