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. 2021 Mar 26;27:588532. doi: 10.3389/pore.2021.588532

TABLE 2.

The top 10 genes with the highest degree between HCC tissues and normal liver tissues.

Gene Description Degree Related signal pathway Up/down
CDK1 cyclin-dependent kinase 1 88 Cell cycle, p53 signaling pathway, Oocyte meiosis Up
CCNB1 cyclin-B1 86 Cell cycle, p53 signaling pathway, Oocyte meiosis Up
AURKA Aurora kinase A 83 Oocyte meiosis Up
CCNA2 cyclin-A2 82 Cell cycle Up
KIF11 kinesin family member 11 82 Not mention Up
BUB1B mitotic checkpoint serine/threonine kinase B 81 Cell cycle Up
TOP2A DNA topoisomerase II alpha 81 Not mention Up
TPX2 Xenopus kinesin-like protein 2 80 Unknown Up
HMMR Hyaluronan mediated motility receptor 80 Not mention Up
CDC45 cell division cycle 45 79 Cell cycle Up

HCC, hepatocellular carcinoma.