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. 2021 Mar 26;27:588532. doi: 10.3389/pore.2021.588532

TABLE 3.

Survival for the ten hub genes in the Asian and White/Caucasian HCC cohorts from TCGA in Kaplan-Meier Plotter.

Gene All (N = 364) White (N = 184) Asian (N = 158)
HR (95%CI) p.Value HR (95%CI) p.Value HR (95%CI) p.Value
CDK1 2.15 (1.52–3.06) 1.1E–05 1.62 (1.01–2.59) 0.042 4.95 (2.63–9.32) 4.7E–08
CCNB1 2.34 (1.55–3.54) 3.4E–05 1.8 (1.1–2.94) 0.018 7.09 (3.29–15.29) 6.3E–09
AURKA 1.77 (1.25–2.5) 0.0011 1.34 (0.84–2.15) 0.22 4.5 (2.33–8.66) 9.6E–07
CCNA2 1.91 (1.36–2.72) 0.00018 1.9 (1.02–3.52) 0.039 5.27 (2.53–10.98) 7.3E–07
KIF11 2.02 (1.42–2.85) 5.5E–05 1.77 (1.11–2.82) 0.014 4.47 (2.44–8.2) 1.3E–07
BUB1B 2.01 (1.42–2.86) 6.6E–05 1.73 (1.01–2.96) 0.042 4.85 (2.64–8.92) 2.4E–08
TOP2A 1.99 (1.39–2.86) 0.00012 2.09 (1.17–3.76) 0.012 5.07 (2.76–9.33) 7.5E–09
TPX2 2.29 (1.62–3.24) 1.4E–06 2.54 (1.34–4.84) 0.0032 5.95 (3.21–11.02) 1.5E–10
HMMR 2.29 (1.62–3.24) 1.3E–06 2.43 (1.45–4.08) 0.00055 4.72 (2.46–9.05) 2.9E–07
CDC45 2.23 (1.51–3.28) 3.4E–05 1.59 (0.99–2.55) 0.053 3.94 (2.16–7.19) 1.6E–06

HCC, hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; HR, Hazard Ratio; CI, confidence interval.