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. 2021 May 10;6(9):e147063. doi: 10.1172/jci.insight.147063

Figure 5. Study design.

Figure 5

A standardized protocol was followed in all study participants. T1-weighted MRI scanning was performed before the intrathecal (Ith) MRI contrast agent injection (Pre), and thereafter standardized T1-weighted MRI sequences were obtained at defined time points at 1, 2–2.5, 4–5, 5–6.5, 22–26, and 46–54 hours. Blood samples for whole blood concentration estimation of MRI contrast agent were obtained in conjunction with each of the MRI acquisitions. Illustration: Øystein Horgmo, University of Oslo.