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. 2021 May 10;6(9):e147789. doi: 10.1172/jci.insight.147789

Figure 1. IgG from patients with LN upregulates CaMK4 in podocytes.

Figure 1

Podocytes in culture were exposed to IgG from individuals with lupus (L) with no kidney involvement, active lupus nephritis (LN), or healthy controls (H). (A and B) CaMK4 mRNA (CaMK4/GAPDH) after RNA extraction (A) and CaMK4 protein expression (representative experiment) (B) from cell lysates was measured. (C) Densitometric quantification of Western blot (CaMK4/GAPDH) data from 3 independent experiments was performed (n = 5 individuals per group, total n = 15).