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. 2021 May 10;6(9):e147789. doi: 10.1172/jci.insight.147789

Figure 5. The presence of galactose on IgG has a protective role in podocyte injury.

Figure 5

(A) CaMK4 expression in podocytes after exposure to untreated IgG and β-galactosidase–treated IgG from healthy controls (H) and individuals with LN. (B) Densitometry was performed for quantification of results in A. (C) Nephrin expression in podocytes after exposure to untreated IgG and β-galactosidase–treated IgG from healthy controls (H) and individuals with LN. (D) Densitometry was performed for quantification of the results in C. Data are shown as mean ± SEM. *P < 0.05; ***P < 0.01, by 1-way ANOVA with Bonferroni post hoc test correction (3 independent experiments utilizing IgG from 3 different individuals were performed for each representative experiment displayed above).