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. 2021 Jun 23;15:697509. doi: 10.3389/fnbeh.2021.697509

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Copyright © 2021 Altshuler, Garcia and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental timeline. We trained adult (P77) and adolescent (P35) rats to self-administer oxycodone for 10 days and tested them for relapse on abstinence days 1 and 15 under either single-housing condition (Experiment 1) or group-housing condition (Experiment 2).