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. 2021 Jun 23;15:697509. doi: 10.3389/fnbeh.2021.697509

FIGURE 5.

FIGURE 5

Effect of housing condition on adult-onset and adolescent-onset oxycodone self-administration, and incubation of oxycodone craving. (A) Data are mean ± SEM number of oxycodone (0.1 mg/kg/infusion) infusions during the ten 6-h daily self-administration sessions for Adult (left) and Adolescent (right). (B) Data are mean ± SEM of active and inactive lever presses during the 30-min relapse test on abstinence day 1 (left) and the 60-min relapse test on abstinence day 15 (right). #Main effect of Housing; *Different from single-housing, p < 0.05. n = 11–25/group.