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. Author manuscript; available in PMC: 2021 Dec 4.
Published in final edited form as: Science. 2021 Jun 4;372(6546):1102–1105. doi: 10.1126/science.abc7303

Fig. 1. Hospitalized dengue disease cases exhibit elevated levels of afucosylated IgG1 glycoforms.

Fig. 1.

(A) Overview of the Fc-associated glycan. (B to C) Analysis of the levels of afucosylated IgG1glycoforms for (B) anti-DENV E-specific and (C) total IgGs from inapparent and hospitalized cases. (D) Correlation of the abundance of afucosylated IgG1 levels of total with DENV E-specific IgGs. (E) Bisecting GlcNAc and (F) galactosylated Fc glycoforms of IgGs from inapparent and hospitalized cases. One-way ANOVA/Bonferroni post-hoc for B, C, E, and F; Pearson correlation analysis for D.