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. Author manuscript; available in PMC: 2021 Dec 4.
Published in final edited form as: Science. 2021 Jun 4;372(6546):1102–1105. doi: 10.1126/science.abc7303

Fig. 2. Afucosylation is associated with dengue disease severity and correlates with biological features of severe disease.

Fig. 2.

(A) Platelet counts and (B) Hct in hospitalized dengue patients with variable clinical classification. (C) Afucosylation levels for total, anti-E, and anti-NS1 IgG1 from dengue patients with variable disease severity. (D to E) Correlation of afucosylated IgG1 levels with platelets and Hct among hospitalized cases. (F) Abundance of afucosylated IgG1 glycoforms in plasma samples from hospitalized patients obtained at the time of admission. (G) ROC analysis assessing the predictive value of the levels of IgG1 afucosylation at admission for severe dengue disease. One-way ANOVA/Bonferroni post-hoc for A to C and F; Pearson correlation analysis for D to E.