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. 2021 Jun 23:NEJMc2107717. doi: 10.1056/NEJMc2107717

Table 1. Numbers of Household Contacts and Secondary Cases of Covid-19, According to Vaccination Status of Index Patient, and Adjusted Odds Ratios.*.

Vaccination Status of Index Patient Household Contacts Secondary Cases Adjusted Odds Ratio
(95% CI)
no. no. (%)
Not vaccinated before testing positive 960,765 96,898 (10.1) Reference
Vaccinated with ChAdOx1 nCoV-19 vaccine ≥21 days before testing positive 3,424 196 (5.7) 0.52 (0.43–0.62)
Vaccinated with BNT162b2 vaccine ≥21 days before testing positive 5,939 371 (6.2) 0.54 (0.47–0.62)
*

Odds ratios were adjusted for the age and sex of the index patient and their household contact, geographic region, calendar week of the index case, and an index of multiple deprivation and household type and size. CI denotes confidence interval, and Covid-19 coronavirus disease 2019.