Figure 1.

TBX5 expression in human and mouse left ventricles. (A) Table showing the information of the individuals from whom ventricular biopsies were obtained. Patients with DCM and ICM in contrast to NF controls, 89% of them suffered from arrhythmias. (B) Representative immunoblot analysis of TBX5 in human left ventricles of DCM, ICM, and NF samples normalized to CASQ2 or GAPDH. Samples loaded on the same blot, but non-contiguously, are indicated by a black line (total sample size: NF n = 7; DCM n = 11; ICM n = 11 biological replicates). Data are presented as mean ± SEM. Statistical analysis was performed by one-way ANOVA with Dunnett’s multiple comparison post hoc test, *P < 0.05, **P < 0.01, ***P < 0.001.