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. 2021 Jun 23;15:696376. doi: 10.3389/fnana.2021.696376

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Copyright © 2021 Ulloa-Navas, Pérez-Borredá, Morales-Gallel, Saurí-Tamarit, García-Tárraga, Gutiérrrez-Martín, Herranz-Pérez and Garcia-Verdugo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fully differentiated oligodendrocytes display Olig2 and APC-(CC1) labeling. (A) Olig2 expression in mature oligodendrocytes is restricted to the uncondensed chromatin within the nucleus in the white matter of a 44-year-old male (PB12). (B) The RNA-binding protein quaking7 labeled with APC-(CC1) was found in the condensed chromatin portion as well as in non-condensed chromatin; faint labeling was also observed in the plasma membrane in the white matter of a 13-year-old female (PB11). N, Nucleus; m, mitochondria. Scale bars: panoramic micrographs, 1 μm; insets: 250 nm.