Figure 7.

Mature oligodendrocytes are electron-dense cells in the human white matter. (A) Mature oligodendrocytes are small electron-dense cells with a broad distribution in the white matter. These cells are intermingled between myelin-wrapped axons. (B) Chromatin condensation occurs bound to the inner nuclear membrane in mature oligodendrocytes. (C) Cytoplasmic organization in this population displays characteristic short dilated endoplasmic reticulum, few mitochondria, dense degradation vesicles, and polyribosomes. The micrograph proceeds from the white matter of a 6-year-old male (PB3) fixed with 2% PFA-2.5% Glutaraldehyde. N, Nucleus; ER, endoplasmic reticulum. Scale bars: (A), 1 μm; (B–C), 250 nm.