. 2021 Apr 24;49(W1):W417–W424. doi: 10.1093/nar/gkab273

Table 1.

Performance comparison of mmCSM-PPI2 on a non-redundant blind test comprising entries with four or more mutations

Method	Pearson	Kendall	Spearman	RMSE (kcal/mol)	MCC	AUC
mmCSM-PPI	0.70	0.48	0.64	2.02	0.53	0.72
Discovery Studio	0.39*	0.29^#	0.41⁺	3.07^a	0.30	0.66
FoldX	0.39*	0.25^#	0.37⁺	5.27^a	0.22	0.61^b

*P-value < 0.05 by Fisher r-to-z transformation test.

^# P < 0.05 by transforming tau-to-r followed by Fisher r-to-z transformation.

⁺ P < 0.05 by transforming rho-to-r followed by Fisher r-to-z transformation.

^a P < 0.05 by Diebold–Mariano test.

^b P < 0.05 by t-test.