Table 1.

Performance comparisons of NetGO 2.0 with its component and competing methods against testing data

	F-max			AUPR			Coverage
	MFO	BPO	CCO	MFO	BPO	CCO	MFO	BPO	CCO
Naïve	0.416	0.256	0.542	0.276	0.118	0.464	1.00	1.00	1.00
Blast-KNN	0.632	0.312	0.566	0.542	0.132	0.405	0.91	0.88	0.81
LR-3mer	0.427	0.258	0.552	0.317	0.125	0.478	1.00	1.00	1.00
LR-InterPro	0.651	0.325	0.641	0.623	0.166	0.587	1.00	1.00	1.00
Net-KNN	0.519	0.325	0.596	0.416	0.192	0.528	0.99	0.99	0.98
RNN	0.524	0.265	0.574	0.424	0.124	0.477	1.00	1.00	1.00
LR-Text	0.464	0.248	0.479	0.353	0.154	0.403	0.72	0.46	0.66
DeepGOPlus	0.620	0.305	0.620	0.521	0.115	0.493	1.00	1.00	1.00
GOLabeler	0.667	0.326	0.631	0.647	0.193	0.557	1.00	1.00	1.00
NetGO	0.674	0.362	0.646	0.653	0.239	0.583	1.00	1.00	1.00
NetGO 2.0	0.666	0.366	0.663	0.655	0.269	0.593	1.00	1.00	1.00