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. 2021 May 5;49(W1):W662–W670. doi: 10.1093/nar/gkab323

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — The Trips-Viz single transcript plot for the human gene POLG (transcript ENST00000268124) using an aggregate of Ribo-Seq reads from multiple studies. The view has been zoomed in around the annotated CDS start. There is a Ribo-seq bias within the first reading frame (red) across the entirety of the ouORF supporting the translation of the correct frame. The ORF architecture beneath the plot (horizontal red, green and blue bars), shows the positions of AUG codons (short white lines), stop codons (longer black lines) and CUG codons (short black lines), making it easier to see the start and stop positions of the ouORF. The third CUG codon in the first reading frame is the translation initiation site of the ouORF (50,51), which has been highlighted in the figure.