A: comparison of tendon biomechanical properties following early and delayed treatment of tendinopathy. Symbols above groups denote statistically significant differences (P < 0.05) compared with all other groups. Horizontal lines denote significant differences between 2 individual groups. Inj, injury; E, early; D, delayed; Trt, treatment. Early muscle-loading treatment significantly decreased cross-sectional area (CSA) and increased material properties relative to untreated injury. No significant differences were observed for structural properties, stiffness, and maximum load (data not shown). B: muscle strength outcomes following 2 wk of early treatment. Errors bars denote means ± SD. Each scatterplot symbol denotes data from an individual mouse Achilles tendon. P < 0.05 was deemed to be statistically significant. *,#Significant differences from all other groups.