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. 2021 May 18;12(3):e00399-21. doi: 10.1128/mBio.00399-21

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Copyright © 2021 Lawrence et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 2 — HIOs mount an acute transcriptional response to Salmonella infection. (A) Principal-component analysis of HIOs injected with S. Typhimurium T3SS mutants. Each circle represents a biological replicate. (B) Sample distance plot of each HIO condition at 2.5 h (gray) and 8 h (black) postinjection. Sample distance was calculated from normalized gene counts across 4 biological replicates. (C and D) Euler diagram comparison of gene changes in each HIO condition relative to PBS-injected HIOs at 2.5 h (C) and 8 h (D) postinjection. Genes were filtered by a P value of <0.05.