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Alignment of HipH and HipT kinases. Sequence alignment of subclades containing HipT of E. coli O127 and HipH of E. coli K-12. Deletions (Δ) and insertions (ω) relative to the HipHE coli K-12 subclade are indicated, as well as the four conserved kinase motifs (Gly-rich loop, activation loop, catalytic motif, and Mg2+-binding motif). HTH domains in the N terminus of HipH kinases are boxed in red.
