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Highly proteolytically active periodontal bacteria degrade the MCPIP-1 protein. Representative Western blot of recombinant human MCPIP-1 protein incubated for 1 h with bacterial supernatants (upper) or bacteria (bottom) classified as pathogens (Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, or Fusobacterium nucleatum) or commensals (Streptococcus oralis, Actinomyces naeslundii, or Streptococcus salivarius).
