Different diets and FMT from mice fed different diets affect the gut microbiota. Feces obtained before (baseline) and after antibiotic treatment (Ab), after FMT (RC-FMT and HFD-FMT), and from donor mice (RC donor and HFD donor) were used in this experiment. (A) Relative abundance of gut bacterial taxa at the genus level in RC-fed (RC donor) and HFD-fed (HFD donor) mice. (B) Relative abundance of gut bacterial taxa at the genus level at baseline, after antibiotic treatment, and after fecal transplantation from RC-fed and HFD-fed mice. (C) Principal coordinate analysis (PCoA) score plot of the gut microbiota profiles of RC-FMT (n = 6) and HFD-FMT (n = 6) mice using unweighted UniFrac distance (ANOSIM). FMT from RC-fed and HFD-fed mice significantly affected recipient gut microbiota. (D) LDA scores from LEfSe analysis of fecal gut microbiota RC- and HFD-fed mice. (E) Pairwise comparisons of significantly changed bacterial taxa between RC-FMT and HFD-FMT mice. **, P < 0.01; Mann-Whitney U-test.