Table 4.

Multivariable logistic regression of factors associated with new morbidity at ICU discharge and multivariable generalized linear model (GLM) of factors associated with moderate to severe disability (FSS ≥ 10 at ICU discharge). Baseline FSS was forced into the models to control for preexisting functional impairment

Risk factors for new morbidity
Variable	Adjusted odds ratio (95% CI)	p-value
Genetic comorbidity	0.02 (<0.01, 0.40)	0.010
Days on sedation (≥ 9)	24.50 (3.01, 199.34)	0.003
Surgery in OR	0.05 (<0.01, 0.56)	0.015
Percent fluid overload	1.03 (1.00, 1.06)	0.067
Risk factors for moderate to severe disability at ICU discharge
	Adjusted odds ratio (95% CI)	p-value
Baseline FSS > 6	0.63 (0.04, 10.02)	0.744
Neurologic comorbidity	20.02 (1.01, 383.75)	0.047
Renal comorbidity	0.03 (<0.01, 0.59)	0.021
Days on sedation	1.14 (0.99, 1.32)	0.067
Percent fluid overload	1.04 (1.0, 1.08)	0.040

FSS, Functional Status Scale; ICU, intensive care unit; OR, operating room