Figure 1. Phylogenetic tree analysis and structural comparison of human, porcine, and mouse IL-7. (A) The phylogenetic tree shows the relationship between human, porcine, and mouse IL-7 protein sequences. The evolutionary history was inferred using the neighbor-joining method. Evolutionary analyses were conducted in MEGA7. (B) The protein sequence homology among human, mouse, and mini-pig IL-7. The protein sequences of porcine, human, and mouse IL-7 were obtained in the FASTA format from the PubMed site. The sequences of the α-helix of human or mouse or porcine IL-7, which constitutes the binding site with IL-7 receptor, was examined by homologous analysis using Clustal Omega.
