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. 2021 Jun 29;2021:5540560. doi: 10.1155/2021/5540560

Table 3.

Association between virulence genes and endoscopic findings in H. pylori strains (no. = 60).

Virulence genes vacA genotypes (No.) Endoscopic findings (n = 60)
PUD (30) No. (%) P value Gastritis (25) No. (%) P value GERD∗∗ (15) No. (%) P value Others (18) No. (%) P value
vacA+/cagA+ s1m1 (26) 10 (33.3%) <0.001 12 (20%) <0.001 8 (13.3%) <0.001 6 (10%) <0.001
s1m2 (5) 5 (16.6%) 4 (6.6%) 2 (3.3%) 0 (0.0%)
s2m2 (1) 1 (3.3%) 0 (0.0%) 1 (1.6%) 0 (0.0%)
vacA+/cagA s1m1 (1) 0 (0.0%) 0.392 1 (3.3%) 0.392 0 (0.0%) 0 (0.0%)
s1m2 (2) 1 (3.3%) 1 (3.3%) 0 (0.0%) 0 (0.0%)
s2m2 (2) 0 (0.0%) 2 (6.6%) 0 (0.0%) 0 (0.0%)
vacA−/cagA 13 (23.3%) 5 (11.6%) 4 (1.6%) 12 (16.6%)

PUD: Peptic Ulcer Disease. ∗∗GERD: Gastroesophageal Reflux Disease.